Allergen Data Collection - Update: Apple (Malus domestica)
Internet Symposium on Food Allergens 2(Suppl.4): 1-23  (2000) [http://www.food-allergens.de]
6.3 Properties of Thaumatin-homologue Protein (Mal d 2)

6.3.1 Molecular Biological Properties
 
Thaumatin-homologue Protein References
Allergen Nomenclature Mal d 2 (1) Larsen & Lowenstein 1999
Molecular Mass 
31 kDa (SDS-PAGE, 1)
(1) Hsieh et al. 1995
Isoelectric Point 
 
Amino Acid Sequence
N-terminus aa 1-26 (1):
AKITFTNNXPNTVWPGILTGFGQKPQ
(1) Hsieh et al. 1995
Sequence Homology
Antifungal protein PR5 fragment aa 27-43 (thaumatin-like protein from Arabidopsis thaliana): 46% identity to N-terminal sequence (1)
N-terminus of wheat trimatin, oat avematin, and barley thaumatin-like protein: 46% identity to N-terminal sequence (1)
(1) Hsieh et al. 1995

 6.3.2 Allergenic Properties
 
Thaumatin-homologue Protein References
Frequency of Sensitization
IgE-binding to 31-kDa-Allergen in 75% of patients (1)
(1) see 6.1 Sensitization to Apple Allergens

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