6.2 Properties of alpha-Livetin (Chicken Serum Albumin)
6.2.1 Molecular Biological Properties
alpha-Livetin | References | ||||||||||||
Allergen Nomenclature Gal d 5 | (1) Larsen & Lowenstein 2000 | ||||||||||||
Molecular Mass 70 kDa (1, 3), 66 kDa (2) (SDS-PAGE: 2, 3) | (1) Williams et al.
1962
(2) de Blay et al. 1994 (3) Szepfalusi et al. 1994 |
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Isoelectric
Point pI 4.3 - 5.7 (1: livetins), pI 4.6-4.8
(2: serum albumin)
|
(1) Ternes 1989
(2) Miller & Gmeiner 1993 |
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Amino Acid Sequence,mRNA, and
cDNA
|
(1) Sorkina et al. 1976
(2) Gordon et al. 1978 (3) Hache et al. 1983 |
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Posttranslational Modifications
Disulfide bonds 17 disulfide bonds (1) |
(1) SWISS-PROT | ||||||||||||
Biological Function
Serum albumin: binding of water and Ca-, Na-, and K- cations, fatty acids, hormones, bilirubin and drugs; regulation of the colloidal osmotic blood pressure (1) 3 homologous domains: domain I: 8-183 domain II: 202-375 domain III: 394-573 |
(1) SWISS-PROT |
6.2.2 Allergenic Properties
alpha-Livetin | References |
Frequency of Sensitization
IgE-binding to alpha-livetin in 100% of patients with bird feather and egg yolk allergy (1) |
(1) see 6.1 Sensitization to Allergens of Bird's Egg Yolk and Feathers |
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