Matthias BESLER (a, b), Hans STEINHART (a), Angelika PASCHKE (a)
(a) Institute of Biochemistry and Food Chemistry, University of Hamburg,
(b) matthias besler ONLINE PUBLISHER, Hamburg, Germany
|This article reviews recent data on the
stability of cow's milk, hen's egg, fish, crustaceae, and meat allergens
during food processing. Generally, allergens of food origin are stable
and highly potent.
Most severe allergic reactions, including fatal
events, can be due to ingestion of cow's milk, hen's egg, fish, and shrimp.
The allergenicity could be altered potentially by various
procedures such as washing, chopping, mincing, heating, canning, storage,
and ripening. Separation methods may simply reduce the allergen content
of a specific product by e.g. extraction, precipitation, or ultrafiltration.
In comparison heating (dry heating, boiling or cooking) and enzymatic digestion
affect the allergen structure. Cow's milk and hen's egg allergens
retain their allergenicity after common industrial treatments. The production
of hypoallergenic cow's milk infant formulas requires extensive conditions
of hydrolysis, heating, and/or ultrafiltration. Fish and crustaceae are
usually stable to heat treatment, while meat allergens are only partially
heat stable. Fish is partially stable and meat is susceptible to enzymatic
Future investigations should monitor the allergenicity of foods throughout manufacturing processes from source to shelf- products by various analytical and diagnostic methods such as DBPCFC, SPT, RAST, SDS-PAGE immunoblot, and inhibition tests. Especially products containing cow's milk and hen's egg should be evaluated since the latter are common as hidden allergens in various processed foods. Clinical evaluations of processed foods should be conducted in several countries with appropriate numbers of patients with convincing allergy to the native food allergen.
[Introduction] [Milk] [Egg] [Fish] [Crustaceae] [Meat] [Conclusions] [References] [Abbreveations]
Dr. Matthias Besler
matthias besler - ONLINE PUBLISHER
Mildestieg 17, D-22307 Hamburg, Germany