6.2.1 Molecular Biological Properties
 

alpha-Livetin	References
Allergen Nomenclature none
Molecular Mass  70 kDa (1, 3), 66 kDa (2) (SDS-PAGE: 2, 3)	(1) Williams et al. 1962  (2) de Blay et al. 1994 (3) Szepfalusi et al. 1994
Isoelectric Point pI 4.3 - 5.7 (1: livetins), pI 4.6-4.8 (2: serum albumin)	(1) Ternes 1989  (2) Miller & Gmeiner 1993
Amino Acid Sequence, mRNA, and cDNA  Protein Serum albumin SWISS-PROT:  P19121 GenBank: X60688, V00381 Amino Acids N-terminus: DAHK (1* ) 592 aa mRNA precursor 1892 bp cDNA precursor 571 bp (fragment, 2)  *conflict to SWISS-PROT	(1) Sorkina et al. 1976  (2) Hache et al. 1983
Posttranslational Modifications  Disulfide bonds  17 disulfide bonds  (1)	(1) SWISS-PROT
Biological Function  Serum albumin: binding of water and Ca-, Na-, and K- cations, fatty acids, hormones, bilirubin and drugs; regulation of the colloidal osmotic blood pressure (1)  3 homologous domains:  domain I: 8-183  domain II: 202-375  domain III: 394-573	(1) SWISS-PROT

 * alpha-livetin and chicken serum albumin are identical (Williams et al. 1962)

 6.2.2 Allergenic Properties
 

alpha-Livetin	References
Frequency of Sensitization  IgE-binding to alpha-livetin in 100% of patients  with bird feather and egg yolk allergy (1)	(1) see 6.1 Sensitization to Allergens of Bird's Egg Yolk and Feathers