Allergen Data Collection:
Mango (Mangifera indica) .............................................. |
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Authors in alphabetical order [contact
information]
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Abstract
Mango is the second most frequently cultivated tropical fruit worldwide.
Most popular varieties of mango fruits are Tommy Atkins (South Africa),
Osteen (Spain), Eden (Israel), and Ngowe (Kenya). Mango, together with
pistachio and cashew, belongs to the Anacardiae family. All three foods
may cause severe anaphylactic reactions. Immediate type oral symptoms are
most frequently seen after ingestion of mango fruits. Besides allergic
reactions to the fruits, sensitizations to mango pollen and seeds have
been described. The incidence of mango fruit allergy is apparently high
in subjects with "celery-mugwort-spice syndrome" or latex and pollen allergy,
although this fact has not been established by double-blind, placebo-controlled
food challenge (DBPCFC).
Two major mango allergens with 30 and 40 kDa and a 46-kDa-allergen
(putative chitinase) have been identified. Cross-reactivities between mango
fruit allergens and mugwort pollen, birch pollen, celery, carrot, and apple
have been described. Further, latex and avocado allergens cross-react with
mango allergens.
The present data collection reviews detailed information on the
prevalence and symptoms of mango allergy as well as diagnostic features,
sensitization patterns, and the occurrence of cross-reactivities in tabular
form.
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The reference lists of the Allergen Data Collections
are based mainly on searches of Medline and FSTA (Food Science & Technology
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rigor of the studies listed is variable and not subject of critique or
evaluation by the authors or the editor of the Allergen Data Collections.
The reader should be aware of considerable problems in comparing data from
different studies (eg. patient cohorts, diagnostic performances, possible
flaws in allergen preparations and methodologies for allergen characterization)
and is encouraged to review the original publications.
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